2011年10月12日星期三

ICA method based on network studies of acupuncture effect

Title: ICA method based on network studies of acupuncture effectAuthor: Zhang YiDegree-granting units: Xi'an University of Electronic Science and TechnologyKeywords: functional magnetic resonance imaging;; acupuncture;; acupuncture effect;; brain function network;; independent component analysis;; functional connectivity degreeSummary:
Acupuncture is the essence of traditional Chinese medicine, Chinese people's long struggle with the disease experience and concluded, as the Chinese nation's precious cultural heritage in China for thousands of clinical practice history. Acupuncture as an Neodymium Magnets important component of acupuncture can treat a variety of diseases such as arthritis, obesity, stroke sequelae, asthma, drug addiction, etc., can also ease the aches and pains. Its remarkable efficacy and few side effects, acupuncture has been made to popularize and gradually recognized by the international medical community. However, although there are already more than 140 countries and territories have adopted the acupuncture therapy, its mechanism is still not clear. Clear explanation of how the mechanism of action of acupuncture has become a major constraining factor in the development of the theory. As the birthplace of acupuncture, Chinese has inherent advantages of the first to reveal the mechanism of acupuncture treatment in order to better used in medical acupuncture practice, thus promoting the motherland medicine, to promote excellent traditional culture of the motherland. Modern medical imaging technology enables study of acupuncture methods and means more and more past decade, functional magnetic resonance imaging (fMRI) technology because of its non-invasive and real-time to reflect the characteristics of specific functional areas in the brain to external stimuli active under the properties, is widely used in domestic and international vision, http://www.everbeenmagnet.com/en/products/110-sintered-neodymium-magnets sense of hearing and thinking, emotions and other senior cognitive research, various research has been widely recognized internationally.
The thesis of traditional Chinese medicine theory, the use of modern medical point of view and functional magnetic resonance imaging technology, from experimental design models and data processing methods, the role of the neural mechanisms of acupuncture conducted a preliminary exploration. Innovation of this paper are as follows:
Based on previous experimental design model to study the traditional multi-block design based on the mechanism of acupuncture. By analyzing multiple pieces of traditional acupuncture in various stages of the experiment (twist pin and resting) contains the effect of differences found in different stages; innovation to independent component analysis of this data-driven method is introduced to acupuncture Zusanli magnetic resonance imaging study, the acupuncture needles twist when state and acupuncture under the resting state network of brain function before acupuncture, respectively, and the brain resting state functional network comparison and found that brain function changes in the network, resulting in acupuncture during the existence of time-varying characteristics of acupuncture effect conclusions.
The basis of the above studies, this paper introduces a non-recurring event-related experimental design patterns, integrated functional connectivity associated with seed-point analysis and independent component analysis of the two methods studied resting state vision-related acupuncture points (bright points) and non-vision-related acupoint (cross-channel points) on the regulation of brain function networks and found that these two different points of acupuncture points even though it can make a similar brain regions are activated the visual cortex, but showed a time-domain characteristics are inversely related. That these two different points of acupuncture points induce a similar spatial activation patterns, which leads to time-domain adjustment mode is that there are significant differences.
This paper also studied acupuncture on the resting state network under the regulation of brain function and found that acupuncture Zusanli major regulator of the resting brain network group under the "spatial attention" network and visual network, and needle exchange information light and points are under the regulation of the resting state of the "default mode" network, found the strongest of the two brain areas activated in the posterior cingulate and precuneus. Also found that the anterior cingulate and the "default mode" functional connectivity networks significantly enhanced. Thus speculated that the two nuclei in the neural regulation of acupuncture played an important role.Degree Year: 2009

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