Synthesis, Characterization, Spectrometric Properities and Biological Activities Investigiation of Salicyladehyde Schiff-base Complexes

　　Synthesis, Characterization, Spectrometric Properities and Biological Activities Investigiation of Salicyladehyde Schiff-base Complexes
　　Schiff bases and their metallic complexes have been widely investigated for more than a century. These complexes are known as being biologically important activities, and as catalysts. The preface of this thesis focuses on introducing the recent advances in the synthesis and applications of Schiff bases, as well as their complexes、 the advances of their application using as potential antibacterial、 antiviral reagents、 anticancer reagents and enzyme inhibitor etc.The complexes of multidentate amide and Schiff base have been attracted people’s interest for Segment neodymium magnet a long time owing to their direct connection with organism and their special chemical properties.
　　The multidentate chelating ligands containing nitrogen and oxygen heteroatoms have strong abilities with transition metal and rare earth metal cations. This kind of complexes are to coordinate special useful for catalysis, electrochemical activity and so on. They often exhibit better fluorescent properties and may be usefully as fluorescent luminophors. Amide is similar to small peptide. It is the model compound of pankrin and oxidase and is important to simulating the mechanism of vital process. Schiff base is a kind or important ligand too. It can coordinate with most of metal to form complexes. These complexes are widely used in catalysis, medicaments and new materials.In this thesis, more than 9 complexes of Schiff base were synthesized by the reactions of hydrazine hydrate; phenylamine; ethylenediamine; o-phenylene diamine; triethylene-tetramine with salicyladehyde. They were characterized by means of elemental analysis, IR and UV spectra. Single crystal structure of the typical http://www.chinamagnets.biz compounds were determined. The antibacterial activities were also examined. The relationship between structure varying and properties was also discussed preliminarily.The following research was presented in this thesis:Metal complexes of Schiff bases have occupied a important role in the development of coordination chemistry and not many papers ranging from pharmaceutical chemistry to biochemical relevant studies were published during recent years. In this thesis, we report the synthesies and characterizations of a series of salicyadehyde with Schiff base and their complexes. The structure analysis of these Schiff base ligands were by X-Ray, IR,UV. In the DMF solutions with different amount of either the ligands or their complexes, the antibacterial activities against two kind of bacteria were examined. It indicated that the Schiff base ligand is